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While rare, patients with a history of thyroid disease should discuss risks with their doctor

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The Question of Thyroid Cancer The warning in patient leaflets regarding thyroid C-cell tumours stems from early rodent studies

A complementary perspective appears in a 2021 review in CNS Drugs: "Zinc deficiency may impair the therapeutic response to psychostimulants, and correction of deficiency before or during treatment could optimize clinical outcomes." The authors stopped short of recommending universal zinc supplementation, calling for larger RCTs

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