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Common side effects may include: Increased hunger Water retention and joint stiffness Tingling or numbness in the extremities (carpal tunnel syndrome symptoms) Muscle aches Insulin resistance (a significant consideration that requires monitoring) Crucial Warning: The long-term safety of combining these peptides is not well-studied
Moreover, GLP-1R is found in the heart and blood vessels and is beneficial in heart rate, vascular endothelium, atherosclerosis, and hypertension [58, 59]
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Again, side effects from medication are always a consideration and the effects vary widely
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