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In women with PCOS who have vitamin D deficiencies, co-supplementation of calcium and vitamin D has demonstrated improvements in -cell function, TAC, high-sensitivity C-reactive protein (hs-CRP), and glutathione (GSH) levels [142]

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Furthermore, shared events such as the increased prosurvival signaling and changes in regulation of metabolism and calcium dynamics suggest that alterations in both neuronal types could be interpreted as an attempt of the cells to reestablish homeostatic levels of cellular function and neuronal connectivity during aging (Toescu and Verkhratsky, 2007

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