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In the absence of NEM an interfering peak in correspondence of the GS-NEM peak eluting at 4.95 min r.t

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Preclinical data in rodent models showed approximately 37% greater hepatic fat reduction versus tirzepatide-equivalent dosing, a finding cited in multiple human trial design rationales as justification for the Retatrutide vs Tirzepatide superiority hypothesis in hepatic metabolic disease contexts

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