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A 2025 JAMA Psychiatry trial (Hendershot et al.) tested lower-dose semaglutide over nine weeks and found reductions in some laboratory measures with smaller real-world effects, suggesting the higher 2.4 mg dose may matter
There are also large private and public specialist clinics providing care to many patients with diabetes and obesity to a greater extent than in other regions [41]
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Pregnant or breastfeeding women, individuals with kidney or liver disorders, and those allergic to glutathione should avoid this treatment
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