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Urate nephropathy is the result of the deposition of monosodium urate crystals in the renal interstitial tissue
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In numerous animal models, sulforaphane (often administered ip, iv, or sc, rather than po) was shown to exert protective effects on many tissues and organs by activating the Nrf2/ARE-dependent pathway (12)
Desired fractions were collected and distilled off the solvent under reduced pressure