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Firstly, the study was limited to male mice, which may not adequately represent potential sex-based differences in the response to semaglutide treatment
Gastrointestinal Effects and Nutrient Malabsorption Common side effects such as nausea, early satiety, and constipation may further restrict dietary intake and impair nutrient absorption - particularly of fat-soluble vitamins and dietary protein
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One RCT (Liraglutide 1.8 mg) was also at risk of attrition bias due to a significative and asymmetric withdrawal (placebo: 23%
Sourcing or using it outside a clinical trial is unlicensed and potentially unsafe
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