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Therefore, the inhibitors developed for the C467 residue of ASCT2 boast the advantages of high specificity and high potency, which can effectively avoid the loss of competitive inhibition by substrate analog inhibitors due to high substrate concentration
FIGURE 6 Oxidative stress and inflammation are considered fundamental mediators of chronic obstructive pulmonary disease (COPD) pathophysiology (Figure 6)
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Additionally, it has been found that cystathionine -synthase (CBS), glutamic pyruvic transaminase 2 (GPT2) and suppressor of variegation 3-9 homolog 1 (SUV39H1) are related to amino acid metabolism and ferroptosis [72]
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