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Functional GTP cyclohydrolase 1 exists as a homodecamer that consists of two tightly associated dimers that each comprise a pentameric complex of the GTP cyclohydrolase 1 monomers
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As the ER lacks glutathione reductase activity, GSSG must be exported to the cytosol by SLC33A1 to maintain redox homeostasis
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In: Hand MS et al, editors
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