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However, Haptoglobin (Hp) mRNA level was not altered due to BSO treatment

Wrinkles, especially those around the eyes and forehead, tend to soften, and skin elasticity increases

As a central enzyme in the tricarboxylic acid cycle, -ketoglutarate dehydrogenase complex (KGDHC) dysfunction may alter mitochondrial metabolite profiles or trigger the release of specific mitochondrial signaling molecules

Mechanistically, we demonstrated that ferroptosis in TECs promoted kidney fibrosis via TGF-/Smad signaling and increased the production of various profibrotic factors, such as TGF-, CTGF, PDGFB, and FGF2

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