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Ferroptosis also appears to have value in overcoming the resistance mechanisms of apoptosis-resistant tumours, for example in p53 mutated or Bcl-2 overexpressing cancers [253]

However, the potential immunosuppressive effects of JAK inhibitors also pose challenges, particularly in immunocompromised individuals or those with concurrent infections

The antioxidant properties also support collagen production, which is vital for maintaining skin elasticity and firmness

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