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However, tumor cells can remodel TME by several means, including increased immunosuppressive population, reduced infiltration of tumor-inhibitory immune cells, reduced presentation of tumor antigens on MHC molecules, and more, allowing them to evade the immune system ( Figure 3F )

and increased glucose clearance and insulin sensitivity

Because the peptide activates GIPR, GLP-1R, and GCGR within a single molecular framework, it allows researchers to examine how endocrine signaling pathways coordinate metabolic responses across multiple tissues

Zhongguo Dang Dai Er Ke Za Zhi

Maintain overall metabolic and cellular function