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Neither compound is approved for human therapeutic use in this combination

If preferred, sample recovery can be improved and manipulation speed for capturing transient interactions may be increased in a number of ways, by using single-step purification procedure, or opting to use magnetic beads rather than agarose resins for faster wash times

10.1016/j.mito.2017.08.001 91 TodkarK.ChikhiL.DesjardinsV.El-MortadaF.PpinG.GermainM

The concept of ferroptosis as an iron-dependent cell death pathway was later introduced through the detailed characterization of the lethal mechanisms of erastin and (1 S, 3R)-RSL3 (RSL3) [5], which target system xc and GPX4, respectively [18]

In fact, it accounts for only 3% of cases