BPC 157 was studied almost exclusively by the same Croatian team that created it, doing rat study after rat study, while MK-677 was the domain of the Merck Research Laboratories in New Jersey, whose scientists conducted multiple small trials in humans in the 1990s, trying to see if the drug had interesting effects on a variety of surrogate markers
Potga A (2022) Glutathione-mediated conjugation of anticancer drugs: an overview of reaction mechanisms and biological significance for drug detoxification and bioactivation

BPC-157: Best for tendon healing and pain Why it's exceptional for tendons: Specifically studied for tendon healing Accelerates collagen synthesis in tendons Reduces tendon inflammation Improves blood flow to tendons (normally poor) Best for: Achilles tendinitis/tendinosis Tennis elbow (lateral epicondylitis) Golfer's elbow (medial epicondylitis) Rotator cuff tendinitis Patellar tendinitis (jumper's knee) Any tendon pain Dosing for tendons: 250-500mcg twice daily Injectable near tendon for best results 8-16 weeks minimum (tendons heal slowly) May need 12-24 weeks for chronic tendinosis Expected results: Week 4-6: Initial pain reduction Week 8-12: Significant improvement Week 12-24: Major healing for chronic cases TB-500 + BPC-157: Best combo for stubborn tendon issues Why combine: BPC-157: Direct tendon healing TB-500: Reduces inflammation, improves flexibility Synergistic tendon repair Protocol: BPC-157: 500mcg twice daily TB-500: 5-10mg weekly 12-16 weeks minimum Best for chronic tendinosis See our best peptides for tendon repair

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Unlike collagen, which primarily provides structural support, glutathione focuses on cellular protection and detoxification