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A Phase I trial of the small non-peptide GLP-1 receptor agonist danuglipron in 98 patients with type 2 diabetes found that it had a similar glucose-lowering ability as the clinically used GLP-1 receptor agonists and was well tolerated during the 4 week study period [43]

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But none had been isolated with incretin-like properties first described by La Barre which was considered to be ideal for the treatment of type 2 diabetes (Marks Samols

GHK-Cu: a topical powerhouse with regenerative potential Another peptide of considerable interest in dermatological and trichological applications is GHK-Cu, a copper-bound tripeptide composed of glycine, histidine, and lysine