Patients with known allergies should inform practitioners before treatment
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Multiplexing these systems allows measuring oxidative stress and cytotoxicity in the same well with minimal alterations to the protocols
Mechanistically, we reveal that VRK2 inhibition disrupts endoplasmic reticulum (ER)-to-Golgi trafficking of SLC7A11, consequently diminishing GSH biosynthesis and predisposing PC cells to ferroptosis