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2026 Jun 11;189(12):3541-3552.e18

Studies show semaglutide does not significantly alter the pharmacokinetics of contraceptive hormones, and non-oral methods such as implants, IUDs, and injections are completely unaffected by gastric emptying changes

If youre interested in using them for off-label weight maintenance, youll still need to consult with your physician and obtain a valid, current prescription

A: Yes, it can be taken on an empty stomach, particularly pre-workout, but some people may prefer taking it with meals to reduce mild stomach discomfort