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The redox properties of NADs regulate the direction of hundreds of cellular biosynthetic pathways varying from amino acid, lipid and nucleotide synthesis to folate cycle, detoxification reactions of drugs and reactive oxygen species 57
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Figure 8 summarizes the main points of this paper, where we claim that excessive levels of deuterium in the mitochondria due to gut dysbiosis may be the driving force that ultimately results in cardiolipin oxidation and migration to the outer membrane, following its accumulation of deuterium bound to the bis-allylic carbon atoms
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