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Two guide RNAs (gRNAs) were designed for the left sides of the target exon 3 and two gRNAs for the right sides (gRNA1: 5-TCTGCCAAGTTCCAGTTCGTTGG-3, gRNA2: 5-AAGGCGGGTTAGAT-CTAAGCGGG-3, gRNA3: 5-ATTTCCAACAACCAACGAACTGG-3, gRNA4: 5-GAAG-GCGGGTTAGATCTAAGCGG-3)
Notably, heightened cholesterol concentrations have been documented within the dermal tissues of those diagnosed with psoriasis (63)
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