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According to estimates from MedPAC, negotiated rebates for diabetic therapy were equal to or greater than 50% in 2023
In terms of its effects, it appears to impact drinking in ways (though not necessarily mechanisms) similar to naltrexone (FDA-approved) and topiramate (prescribed off label for alcohol use disorder), which have a greater effect in reducing intensity of drinking on drinking days relative to their effects on whether someone drinks at all (i.e., abstinent days) although all of them do increase abstinent days to some degree on average)
Many doctors believe that obesity is a complex issue and are hesitant to prescribe new drugs for general weight loss, according to reports
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