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Note that in a larger set of 77 human coronaviruses, a serine (S) in P4 is very common (12), and in addition the sequence SI in the TXNRD1 site is isosteric to TV, the aligned residues in the nsp12/13 site, because transfer of a methyl group from threonine to valine would result in serine and isoleucine

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Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto's thyroiditis: A prospective randomized-controlled trial

A dynamic balance is maintained between the synthesis, consumption, and transport of GSH, all of which determine its intracellular concentration

Biomolecules 10 , 358 (2020)