Co-infusion of GLP-1 and GCG has been shown to reduce glucagon-induced hyperglycemia, lower blood glucose levels, suppress food intake, and enhance energy expenditure in both diabetic obese mice and healthy human volunteers [78]
Laboratory investigation typically includes comprehensive metabolic panel, magnesium level, creatine kinase (if muscle injury is suspected), and possibly vitamin D level
B12 therapy may also support healthy immune function, and some studies have even suggested that it may reduce the risk of certain types of cancer
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Because it shares pharmacological features with licensed GLP-1 receptor agonists such as semaglutide and tirzepatide, clinically relevant interactions including with antidiabetic medicines, anticoagulants, and narrow therapeutic index drugs can be anticipated