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This pattern is entirely in line with large contemporary cohorts showing albumin-bilirubin (ALBI) indices and hypoalbuminemia as powerful markers of hepatic reserve and survival in cirrhosis, including ICU and sepsis settings ( The most intriguing, and potentially important finding is the clear link between inflammatory burden, inflammatory trajectory, and likelihood of MELD-3 improvement
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Zepbound received FDA approval for moderate-to-severe obstructive sleep apnea in adults with obesity in December 2024, and Wegovy gained a cardiovascular risk reduction indication for patients with established heart disease and obesity
Insurance plans could still require step therapy, prior authorization, or restrictive eligibility criteria
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