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To explore the potential impact of titration timing on clinical outcomes, early and late escalation groups were defined using the cohort median as the cutoff, as there is presently no established clinical consensus defining rapid versus delayed escalation
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The Stack Regeneron's Phase 2 COURAGE trial combined semaglutide with trevogrumab, an antibody that blocks myostatin, the protein that signals muscle to stop growing
At the same time, it could focus the pharmacare debate on drugs that are fiscally positive investments
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