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Failure of autophagy in this context promotes the accumulation of oxidative stress, aberrant signaling, mitochondrial damage, and chronic inflammation, collectively establishing a pro-tumorigenic cellular environment

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2.5.1 Multi-omics approaches and systems biology in Alzheimers research Recent advances in multi-omics technologiesincluding transcriptomics, metabolomics, proteomics, and spatial transcriptomicshave opened new avenues for elucidating the molecular mechanisms through which natural products influence AD pathogenesis (Ma et al., 2024a)