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This is clinically favorable (improved drug metabolism) but creates a transient period of unpredictable pharmacokinetics during active fibrosis regression

This leads to natural reductions in food intake and cravings for high-sugar, high-fat foods

While those numbers are worth noting, theyre comparable to or lower than what is observed with Semaglutide (which saw 7-11% discontinuation across trial arms) and suggest manageable tolerability for most participants