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Quick Answer: Tirzepatide does not have established direct interactions with antibiotics according to FDA prescribing information
Diabetes, Obesity and Metabolism , 25(6), 1534-1545
In another study, Xie et al
Science (2013) 342(6155):1242454
However, some people may notice increased urination during treatment, particularly if blood sugar levels improve, fluid intake increases, or gastrointestinal side effects such as vomiting or diarrhea lead to greater hydration needs
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