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PLoS ONE 11 , e0160264 (2016)
Grassley CE, Wyden R, Insulin: Examining the Factors Driving the Rising Cost of a Century OldDrug
The discrepancy between the values of the IOM and those of recent studies on healthy people may be explained by the fact that the former represent minimal arithmetic values that assume an optimal uptake in completely healthy people, whereas the current studies represent practically determined values, which take into account real-life fluctuations
Although these data are promising, larger studies with longer duration of treatment with DPP-4 inhibitors are needed to evaluate whether efficacy is sustained in the longer term
, Yor-Aguilar, M
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