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Methionine is then converted into S-adenosylmethionine, which donates methyl groups in reactions catalyzed by methyltransferases, including DNA methylation, producing S-adenosylhomocysteine that is converted back into homocysteine

NDI1 overexpression has been shown to rescue CI deficiency and limit the effects of mitochondrial dysfunction 48

IGF-1 is further thought to mediate the majority of GH's anabolic effects, such as the potential for lean body mass increase

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