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Chen Y, Deng J, Fujimoto J, Kadara H, Men T, Lotan D, et al

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Recently, a surfactant conjugated co-agonist peptide 17 was shown to have a half-life of 52 hours in vivo and at a higher dose led to 40% body weight loss in obese rats over 27 days (79)

However, LOsG impaired glucose tolerances (GT), as revealed by OGTT and decreased fast plasma insulin level (Fig