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When Cartman is denied access to the life-changing medicine, the kids jump into action. It will be the seventh special episode that South Park has produced, with others previously focussing on topics like Covid and streaming

Study participants were randomly assigned in a 2:1:1:1:1:2:2 ratio to receive subcutaneous retatrutide 1 mg, 4 mg (starting dose 2 mg), 4 mg (starting dose 4 mg), 8 mg (starting dose 2 mg), 8 mg (starting dose 4 mg), 12 mg (starting dose 2 mg) or placebo once weekly for 48 weeks

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That is a meaningful difference, especially at lower doses where the gap between effective and subtherapeutic is narrow