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In adults with type 2 diabetes, treatment with tirzepatide 5 mg, 10 mg and 15 mg once weekly was associated with superior weight reduction from baseline compared with placebo, semaglutide 1 mg weekly, titrated insulin degludec, titrated insulin glargine and titrated insulin lispro as an add-on to insulin glargine
This enhancement in gut health is associated with improved cognitive performance and reduced systemic inflammation, suggesting that the neuroprotective effects of semaglutide are partially mediated by this complex axis (Feng et al., 2024)
difficile ) DHPPA (beneficial bacteria) Glyceric Acid Glycolic Acid Oxalic Acid Lactic Acid Pyruvic Acid 2-Hydroxybutyric Acid Fumaric Acid Malic Acid 2-Oxoglutaric Acid Aconitic Acid Citric Acid Homovanillic Acid (HVA) Vanillmandelic Acid (VMA) HVA/VMA Ratio 5-Hydroxyindoleacetic Acid (5-HIAA) Quinolinic Acid Kynurenic Acid HVA/DOPAC Ratio Dihydroxyphenylacetic (DOPAC) Uracil Thymine 3-Hydroxybutyric Acid Acetoacetic Acid 4-Hydroxybutyric Acid Ethylmalonic Acid Methylsuccinic Acid Adipic Acid Suberic Acid Sebacic Acid Methylmalonic Acid (Vitamin B12) Pyridoxic Acid (Vitamin B6) Pantothenic Acid (Vitamin B5) Glutaric Acid (Vitamin B2-Riboflavin) Ascorbic Acid (Vitamin C) 3-OH-3-Methylglutaric Acid (Vitamin Q10/CoQ10) N-Acetylcysteine (Glutathione precursor and chelating agent) Methylcitric Acid (Vitamin H-Biotin) Pyroglutamic Acid Orotic Acid 2-Hydroxyhippuric Acid 2-Hydroxyisovaleric Acid 2-Oxoisovaleric Acid 3-Methyl-2-oxovaleric Acid 2-Hydroxyisocaproic Acid 2-Oxoisocaproic Acid 2-Oxo-4-methiolbutyric Acid Mandelic Acid Phenyllactic Acid Phenylpyruvic Acid Homogentisic Acid 4-Hydroxyphenyllactic Acid N-Acetylaspartic Acid Malonic Acid 3-Methylglutaric Acid 3-Hydroxyglutaric Acid 3-Methylglutaconic Acid Phosphoric Acid Sample Reports The OAT test report is organized into six clinically useful categories including: Microbial Overgrowth Markers of yeast, mold, bacteria, Clostridium species, and their metabolic byproducts. Mitochondrial Health Intermediates of glucose, fatty acid, and amino acid metabolism involved in energy production Neurotransmitter Metabolites Dopamine, serotonin, and norepinephrine/ epinephrine pathway metabolites, providing insights into neurotransmitter imbalances. Toxic Exposure Direct and indirect biomarkers reflecting the functional demand for B-vitamins, antioxidants, and other key micronutrients. Methylation / Detoxification Metabolites reflecting methyl group cycling, glutathione status, and nutrients involved in both methylation and detoxification. Nutrient Needs Direct and indirect biomarkers reflecting the functional demand for B-vitamins, antioxidants, and other key micronutrients
Tirzepatide works through whats known as incretin biology, which is our hormonal response system to control glucose levels and appetite following meals
Contraindications In generally fit & healthy clients, fat dissolving is a relatively safe & effective treatment
