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Even though semaglutide can modestly raise resting pulse, large cardiovascular outcome trials have shown cardiovascular benefit with GLP-1 receptor agonists

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Starting at the maximum dose would produce intolerable nausea in most patients

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There is a therapeutic window

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Biomarker Assessment and Baseline Status Matter Before considering NAD and glutathione support, baseline measurement of these moleculesthrough blood work, saliva panels, or mitochondrial function testscan reveal whether depletion is actually present

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doi: 10.1016/j.fct.2023.113914 109 WernerCSchirmerSGenschCPavlickovaVPssJWrightMet al

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