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Side Effects Compared Both share similar GI side effect profiles since they both activate GLP-1 receptors: Tirzepatide generally shows lower GI side effect rates in trials, possibly because GIP receptor activation provides a "smoother" signaling profile than pure GLP-1 agonism
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Why what you eat on GLP-1s is important When we have lower hunger levels and were in a calorie deficit, every meal needs to provide enough protein, fibre, and essential nutrients to keep our energy stable, support our immune system, and maintain our muscle mass
Result: Reduced calorie intake naturally without needing strict diets
Watch the Gap : Limit fats to 30% of your energy to manage calorie density
