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Studies confirmed that animals lacking these receptors showed no lipolytic response, validating this as the primary pathway
Generally, however, the matter may come down to a question of scope
[3] Use of the drug for performance enhancement is not currently approved by the FDA
In the 2021 Nature Metabolism study, mice treated with 5-Amino-1MQ showed 35% reduction in white adipose tissue mass without caloric restriction, alongside improved insulin sensitivity and reduced hepatic steatosis
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