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Apoptosis 25(1112):786798 Funding This work was supported by the National Natural Science Foundation of China (U2004118, 81972479), Natural Science Foundation of Guangdong province (2024A1515010310), Henan Natural Science Foundation (202300410359, China) and Henan Medical Program (SBGJ2020002081, China), Science and Technology Research Projects of Henan Province (242102310059), The Innovation Project of Universities in Guangdong Province (NO