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Phase 3 trial protocols allow dose reduction at lower BMI levels rather than stopping treatment

Many of the neuroprotective, neurodegenerative, psychiatric, and addiction-related applications discussed remain investigational, and no GLP-1 receptor agonist is currently approved by regulatory authorities for the treatment or prevention of Alzheimers disease, Parkinsons disease, depression, substance use disorders, or other neurological indications unless specifically stated otherwise

Thats of particular concern because its not uncommon for individuals with dementia to forget to eat and drink regularly or have difficulty communicating their need for water and food to caregivers, she says

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