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showed that a 12-week administration of semaglutide in HFD-induced NAFLD mice reduced body weight, glucose, insulin resistance, LFTs, serum lipids, inflammatory markers [TNF-, interleukin (IL)-6, IL-1], and oxidative stress markers [malonaldehyde (MDA)], thus improving hepatic steatosis, inflammation, mitochondria damage, and fibrosis
using the peptide beyond 28 days introduces variables related to oxidation that can confound sensitive metabolic data
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We expect to see these medications prescribed for a broader range of indications, including osteoarthritis, cardiovascular disease, and chronic kidney disease
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