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Moreover, OA increased the numbers of cells with the pyroptosis morphology as cell swelling with large bubbles (Figure 9F), increased the levels of full-length and cleaved forms of GSDMD (Figure 9G) and GSDME (Figure 9H), these indicated that OA elicited pyroptosis in HepG2 cells, which were all inhibited by H 2 -rich medium treatment
The presence of funnel plot asymmetry also suggests potential publication bias, which warrants further scrutiny
Development actually halted in 2007 because results across 536 subjects over 24 weeks did not reach statistical significance for the primary endpoint
Predrag Sikiric is listed in [9] and [16] under the referenced citations
Ongoing studies are exploring the potential of glutathione in treating various health conditions, from neurodegenerative diseases to autoimmune disorders
