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TennCare has covered GLP-1 precursors and their counterparts since they became FDA approved in 2005 as add-on therapy for diabetes management, and cardiovascular disease mid-year 2024, consistent with federal requirements and TennCare Medical Necessity Rules
It works by modulating the balance of neurotransmitters, particularly serotonin and dopamine
Clinical implication Clinicians are encouraged to perform comprehensive evaluations prior to prescribing GLP-1 RA therapy in patients with a history of pancreatic disorders or other pancreatitis risk factors
Some reported or potential side effects include nausea, facial flushing, decreased appetite, headache, fatigue or drowsiness, yawning/stretching, injection-site irritation, and changes in arousal or spontaneous erections
For extended air travel, USB-powered coolers with dual-mode operation offer the most reliable protection
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