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Table 1: More approval challenges Both the US and the EU continue to face challenges that may influence the nature and timing of new drug approvals, both now and in the future

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And: It primarily affected people with a specific anatomical peculiarity of the optic nerve head, a so-called Crowded Disc . A Crowded Disc refers to a congenital anatomical configuration of the optic nerve head (papilla) where the opening in the eyeball through which the optic nerve exits the eye is very narrow relative to the thickness of the optic nerve

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