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However, the NAC monotherapy arm (600 mg three times daily) showed a trend toward slower decline in forced vital capacity (FVC) that did not reach statistical significance compared to placebo (Martinez et al., N Engl J Med, 2014) [45]
Look for jaundice in conjunctivae, nail beds, and sublingual mucosa
Mitochondrial dysfunction in Alzheimers disease
Mediation analysis from the STEP trials found that of the additional 7.6-14.4% weight loss achieved with semaglutide versus placebo, less than 1 percentage point was mediated by gastrointestinal adverse events
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Toan ATN, Phung TL, Dang TT, et al
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