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FDA regulatory context: As of May 2026, the FDA has proposed excluding compounded semaglutide and tirzepatide from the 503B Bulks List, with a public comment period closing June 29, 2026
Joint pain has been reported with GLP-1 use, though its less common than muscle soreness
How did its reputation for skin whitening spread so far
Many patients report feeling satisfied with smaller portions, fewer cravings, and more control around food decisions
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