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A 2022 Cell Metabolism publication describes LY3437943 as a novel triple agonist peptide with in vitro activity at GCGR, GIPR, and GLP-1R

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Many or most cases are idiopathic

GZFLW is able to significantly increase the expression of 14-3-3, TSC2, and FOXO in human primary uterine leiomyoma cells as compared to the nontreatment group, which suggests the possible pathway of GZFLW in inhibiting proliferation and inducing apoptosis (Shen et al., 2016)