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PloS Pathog
Using erastin-treated A549 cells, we measured intracellular Fe 2+ , ROS, lipid peroxide, glutathione, glutamate release into the extracellular space, and cystine uptake
This material is a research chemical for in-vitro laboratory use only
GSH-responsive nanomedicine offers solutions through site-specific activation, controlled drug release, and selective amplification of redox-dependent cytotoxicity within tumors, enhancing efficacy while reducing off-target effects
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