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In the wake of the success of GLP-1s, drug companies are scrambling to develop, test, and bring to market more behavior-supporting drugs
Notably, semaglutide treatment was associated with a reduction in proteins upregulated in neuropathic pain and an increase in proteins typically downregulated in such conditions, further supporting the potential therapeutic benefits of semaglutide in managing neuropathic pain [67]
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Preclinical studies have consistently shown that targeting ferroptosis with drugs such as iron chelators, lipid peroxidation inhibitors or NRF2 activators can produce significant neuroprotective effects
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