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For a broader view of peptide pharmacology and why some molecules tolerate long-acting formats better than others, see our reference on peptide pharmacology and profiles such as semaglutide (weekly), which illustrates why extended exposure often comes with GI tradeoffs

doi:10.1111/j.1463-1326.2008.01018.x 36

Platelets 31 , 627632 (2020)

There are interesting new developments in the control of ryanodine receptors by accessory proteins, the latest of which is the proposed role of leaky RyR channels in causing delayed afterdepolarizations, a cause of lethal ventricular arrhythmias

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