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Another study showed that NLRP3 inflammasome activation promoted lung dysfunction by triggering alveolar macrophage pyroptosis in pancreatitis progression (Wu et al., 2020)

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In an acyclic ewe model with intravenous LPS administration, Herman and Tomaszewska-Zaremba (2010) demonstrated that LPS treatment significantly suppressed GnRH and its receptor messenger RNA (mRNA) expression in the hypothalamic preoptic area and median eminence (by 4060% and 50%, respectively

Endocrine reviews, vol

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