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Microglial and astrocytic proteins are preferentially elevated in the GCLC-KO mouse brain To uncover mechanisms leading to brain atrophy in GCLC-KO mice, we next performed a comprehensive analysis of protein expression by Liquid Chromatography-Mass spectrometry (LCMS) analysis using brain samples from 4-month-old GCLC-KO mice (Fig
These results revealed the complicated regulation of LOX by the sex hormones and indicated a potential target in manipulating organogenesis through LOX regulation
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How long KLOW stays in the system functionally extends beyond serum detectability through tissue-level receptor binding and downstream pathway activation
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