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48 Hence, breast carcinogenesis is a multistep process involving the accumulation of genetic alterations and the influence of various risk factors

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By contrast, an eccDNA that is implicitly considered large is uniquely described as the eccDNA replicon (Koo et al., 2018

These free radicals, generated as byproducts of normal metabolic processes or introduced through external factors like pollution and UV radiation, can damage cells and contribute to various skin and health issues